• The LHC has commenced its 2025 physics data-taking campaign with proton collisions at 13.6 TeV, targeting luminosity similar to 2024.
• Experiments ALICE, ATLAS, CMS, and LHCb underwent maintenance and upgrades during the year-end technical stop (YETS) in preparation for the 2025 run.
• The 2025 campaign will feature proton collisions, the LHC's first oxygen ion run in July, and a lead ion campaign in October and November.

The Large Hadron Collider (LHC) has initiated its 2025 physics data-taking campaign, marking the fourth year of Run 3. The campaign begins with proton collisions at 13.6 TeV, and experiments are striving for integrated luminosity targets comparable to those achieved in 2024. The program includes proton-proton collisions, a first-ever oxygen ion run in July, and a lead ion campaign later in the year. The start of the physics campaign was preceded by a year-end technical stop (YETS) where significant maintenance, optimizations, and upgrades were carried out across the LHC's four main experiments.

• What: The LHC has restarted its physics data-taking campaign for 2025, following a year-end technical stop for maintenance and upgrades. The campaign will include proton collisions, an oxygen ion run, and a lead ion campaign.
• Who: The key entities involved are the Large Hadron Collider (LHC), CERN, and the four main experiments: ALICE, ATLAS, CMS, and LHCb.
• When: The 2025 physics data-taking campaign started on May 5, 2025. The lead ion campaign will take place in October and November. The oxygen ion run is scheduled for July. Run 3 started in 2022 and will end in 2026.
• Where: The events are taking place at the Large Hadron Collider (LHC) at CERN.

The resumption of the LHC's physics data-taking campaign for 2025 is a significant event for particle physics. The ambitious luminosity targets set for the experiments suggest a strong push for data collection. The first-ever oxygen ion run in July represents a novel experimental opportunity. The extensive maintenance and upgrade work performed during the YETS across all four major experiments highlights the ongoing efforts to improve the performance and capabilities of the LHC.

The LHC's 2025 physics season is now underway, with experiments poised to collect substantial data following extensive maintenance and upgrades. The campaign includes proton collisions, an oxygen ion run, and a lead ion campaign, all aimed at furthering our understanding of fundamental physics. The success of this run will depend on achieving the ambitious luminosity targets and the stable operation of the upgraded detectors.